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Week 1-4: Initial response (starting dose titration) Physical changes: 4-8 pounds weight loss (mostly water and reduced food volume in system) Appetite dramatically reduced Less frequent hunger signals What photos show: Minor changes

Again, RF microneedling or fractional laser strengthens the dermal scaffolding along the jawline and under the chin while Polynucleotides or Profhilo can enhance elasticity in this area, preventing that fine, crpe-like laxity in the areas around the mouth that filler alone cannot correct

Heres how: Antioxidant Properties : Glutathione can help mitigate oxidative stress, which has been linked to increased uric acid production

GPs can prescribe B12 injections following appropriate investigation, which should include: Full blood count to identify macrocytic anaemia Serum B12 and folate levels to confirm deficiency (using laboratory-specific reference ranges) Methylmalonic acid and/or homocysteine when B12 results are borderline Intrinsic factor antibodies if pernicious anaemia is suspected Additional tests depending on clinical presentation (e.g., thyroid function, coeliac serology) When both B12 and folate deficiency are present, B12 should be replaced before folate to avoid precipitating subacute combined degeneration of the spinal cord